Nothing enters a protocol without evidence
Interventions are graded: peer-reviewed canine trials first, then comparative mammalian data, then clinical consensus. Anything below that line is labelled experimental and discussed openly.
Science
Rigour is the product. Everything else is service.
Thought-leadership partner
University of Pennsylvania School of Veterinary Medicine
Penn Vet is our thought-leadership partner: its clinicians and researchers help shape how we read canine ageing, which markers earn a place in the panel, and where the evidence is still thin. The partnership is advisory and academic, it sets the standard our protocols are held to rather than delivering care itself.
Founded in 1884, the School of Veterinary Medicine at the University of Pennsylvania is the only veterinary school in the United States with a direct link to a university school of medicine, which is why its work on comparative medicine translates so readily between species. It runs two campuses: the Philadelphia campus with the Ryan Veterinary Hospital for companion animals, and New Bolton Center in Chester County for large animals. Its faculty publish through Bellwether magazine and the Penn Vet research centres and institutes that sit alongside the teaching hospitals.
- Advisory review of the eleven-system diagnostic panel
- Guidance on canine oncology surveillance and sports medicine
- Annual scientific roundtable with member-cohort findings
Penn Vet by the numbers
1884
Founded, one of the oldest veterinary schools in the United States
59k+
Animals treated each year across its hospitals and local farms
95%
North American Veterinary Licensing Examination pass rate, class of 2025
6
Research centres and institutes alongside the teaching hospitals
Evidence standards
Four rules we do not bend.
Biological age beats chronological age
A seven-year-old Great Dane and a seven-year-old terrier are not the same animal. Every system is scored against breed- and size-matched reference curves.
Measurement is repeated, not one-off
A single panel is a snapshot; two panels a year make a trajectory. Trajectories are what we actually treat.
Outcomes are published to members
Aggregate, de-identified cohort results are reported annually, including where protocols failed to move a marker.